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Washington, Nov 5 (PTI) Air pollution may have detrimental effects on heart in individuals with hypertension and kidney disease, according to a study.<\/p>\n
The researchers found that in adults with chronic kidney disease (CKD) in addition to hypertension, air pollution exposure was associated with rising levels of Galectin 3, a marker of scarring in the heart.<\/p>\n
The findings were presented online at the American Society of Nephrology (ASN) Kidney Week 2021 on Thursday.<\/p>\n
“Air pollution may be directly linked to the development of myocardial fibrosis in individuals with CKD,” said study lead author Hafsa Tariq, from Case Western Reserve University in the US.<\/p>\n
Myocardial fibrosis arises when a type of cell in the heart called fibroblasts produce collagenous scar tissue. It can lead to heart failure and death.<\/p>\n
“Efforts to limit air pollution could have a beneficial effect on lowering subclinical cardiovascular disease in CKD,” Tariq said.<\/p>\n
Satellite-derived measurements of smaller particulate matter, PM2.5, were linked with participants in the Systolic Blood Pressure Intervention Trial.<\/p>\n
A total of 1,019 participants with available Galectin 3 levels at study baseline and 24 months follow-up were included in these analyses.<\/p>\n
The researchers adjusted for age, sex, race and body mass index, among many other factors to assess the association between air pollution and Galectin 3 at baseline and longitudinal change at two years.<\/p>\n
The study concluded that air pollution may be associated with worsening myocardial fibrosis as evidenced by increasing levels of Galectin 3 in individuals with preexisting CKD.<\/p>\n
The researchers noted that further studies are needed to corroborate these findings with rigorous cardiac imaging studies.<\/p>\n","protected":false},"excerpt":{"rendered":"
Washington, Nov 5 (PTI) Air pollution may have detrimental effects on heart in individuals with hypertension and kidney disease, according to a study. The researchers found that in adults with chronic kidney disease (CKD) in addition to hypertension, air pollution exposure was associated with rising levels of Galectin 3, a marker of scarring in the […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[15],"tags":[],"class_list":{"0":"post-176003","1":"post","2":"type-post","3":"status-publish","4":"format-standard","6":"category-world"},"_links":{"self":[{"href":"https:\/\/arunachaltimes.in\/index.php\/wp-json\/wp\/v2\/posts\/176003","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/arunachaltimes.in\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/arunachaltimes.in\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/arunachaltimes.in\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/arunachaltimes.in\/index.php\/wp-json\/wp\/v2\/comments?post=176003"}],"version-history":[{"count":0,"href":"https:\/\/arunachaltimes.in\/index.php\/wp-json\/wp\/v2\/posts\/176003\/revisions"}],"wp:attachment":[{"href":"https:\/\/arunachaltimes.in\/index.php\/wp-json\/wp\/v2\/media?parent=176003"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/arunachaltimes.in\/index.php\/wp-json\/wp\/v2\/categories?post=176003"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/arunachaltimes.in\/index.php\/wp-json\/wp\/v2\/tags?post=176003"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}